Fluoride 2000 May 33(2): 74-78.
Effect of High-Fluoride Water on Intelligence in Children
Lu Y, Sun ZR, Wu LN, Wang X, Lu W, Liu SS
Department of Environmental Health, Tianjin Medical University, Tianjin, China. email@example.com
The Intelligence Quotient (IQ) was measured in 118 children, aged 10-12 years, who were life-long residents in two villages of similar population size and social, educational and economic background but differing in the level of fluoride in drinking water. The children in the high-fluoride area (drinking water fluoride 3.15 + 0.61 mg/L [ppm]) (mean + S.D.) had higher urinary fluoride levels (4.99 + 2.57 mg/L) than the children in the low-fluoride area (drinking water fluoride 0.37 + 0.04 mg/L) (urinary fluoride 1.43 + 0.64 mg/L). The IQ of the 60 children in the high-fluoride area was significantly lower, mean 92.27 + 20.45, than that of the 58 children in the low-fluoride area, mean 103.05 + 13.86. More children in the high-fluoride area, 21.6%, were in the retardation (<70) or borderline (70-79) categories of IQ than children in the low fluoride area, 3.4%. An inverse relationship was also present between IQ and the urinary fluoride level. Exposure of children to high levels of fluoride may therefore carry the risk of impaired development of intelligence.
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